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Tinnitus Treatment Research: Memantine Drug Therapy

Written by AudioNotch Team on November 07, 2012


An interesting new paper has shown evidence that the administration of memantine, a drug that block NMDA-type glutamate receptors, may reduce the volume of chronic tinnitus. The research was performed in animals, although tinnitus response was measured by an indirect correlate (tinnitus-associated behaviour). Click here for the paper.
We re-investigated the effects of memantine on the behavioral manifestations of tinnitus induced by acoustic trauma (a 16-kHz, 110-dB pure tone presented unilaterally for 1 h) in rats. We used a conditioned lick suppression model in which lick suppression was associated with the perception of high … Continue Reading