Category: Tinnitus Research
Anything on recent research into tinnitus.
42 posts in this category
AudioNotch Went Through a Randomized Controlled Trial. Here's What Happened.
Written by Adrian Green on July 16, 2026
Categories: TinnitusTinnitus Research
Tags: notched sound therapy tinnitus research clinical trial audionotch
Northwell Health researchers randomized 65 tinnitus patients to AudioNotch or standard care and followed them for a year. The results, the caveats, and what they actually mean, with the full citation trail.
Ranked: Sound Therapies for Tinnitus
Written by Adrian Green on March 17, 2026
Categories: TinnitusTinnitus TreatmentTinnitus Research
Tags: sound therapy notched sound therapy tinnitus research tinnitus treatment
An honest, evidence-based ranking of every major sound therapy for tinnitus -- from CBT and hearing aids to notched sound therapy, bimodal neuromodulation, TRT, and more. What works, what might work, and what probably doesn't.
How Sound Retrains the Tinnitus Brain: The Neuroscience of Neuroplasticity-Based Therapy
Written by Adrian Green on February 23, 2026
Categories: TinnitusTinnitus ResearchTinnitus Treatment
Tags: neuroplasticity tinnitus research notched sound therapy sound therapy
If tinnitus is created by the brain rewiring itself, can we fix it by rewiring the brain back? Two decades of research into neuroplasticity-based sound therapy -- from notched sound to bimodal neuromodulation -- are starting to provide answers.
Brain Training Outperforms Talk Therapy for Tinnitus: What a New Clinical Trial Found
Written by Adrian Green on February 18, 2026
Categories: TinnitusTinnitus ResearchTinnitus Treatment
Tags: tinnitus research neurofeedback fmri cbt
A clinical trial found that real-time fMRI neurofeedback - where patients learn to control their own brain activity - reduced tinnitus distress significantly more than cognitive behavioral therapy, with benefits that kept growing over 12 months.
Harvard Researchers Discover Objective Biomarkers for Tinnitus
Written by Adrian Green on January 6, 2026
Categories: TinnitusTinnitus Research
Tags: tinnitus research biomarkers harvard
Researchers at Harvard Medical School and Massachusetts Eye and Ear have identified objective, measurable biomarkers for tinnitus severity - and the implications for treatment development could be significant.
The Definitive Guide To Detecting Your Tinnitus Frequency
Written by AudioNotch Team on September 1, 2019
Categories: TinnitusTinnitus Research
Tags: AudioNotch tinnitus frequency matching tinnitus tuning
Detecting your tinnitus frequency isn't easy. Data shows that about fifty percent of users will be able to consistently and reliably identify a tinnitus frequency that matches their own. This process is called "pitch-masking," "frequency-matching," or "tinnitus tuning" (all of these terms are interchangeable). The...
Tinnitus and Ketamine
Written by AudioNotch Team on March 30, 2018
Categories: DoctorTinnitusTinnitus ResearchTinnitus Treatment
Tags: Tinnitus tinnitus and depression tinnitus cure tinnitus treatment
Please note: the following information does not constitute professional medical advice, and is provided for general informational purposes only. Please speak to your doctor if you have tinnitus. With one in five Americans suffering from chronic ringing in the ears, better known as tinnitus, there's no doubt this is a...
Evidence for Notched Sound Therapy: Does it Actually Lower Tinnitus Volume?
Written by AudioNotch Team on June 9, 2017
Categories: TinnitusTinnitus ResearchTreatment Review
Tags: notched sound therapy Tailor-Made Notched Music Therapy Tailor-Made Notched Sound Therapy tinnitus treatment
Please note: the following information does not constitute professional medical advice, and is provided for general informational purposes only. Please speak to your doctor if you have tinnitus. Here's a summary of experimental research that has demonstrated a reduction in tinnitus volume with Notched Sound Therapy:...
What are the most common tinnitus frequencies?
Written by AudioNotch Team on June 24, 2015
Categories: Tinnitus Research
Tags: tinnitus frequency distribution What are the most common tinnitus frequencies?
Please note: the following information does not constitute professional medical advice, and is provided for general informational purposes only. Please speak to your doctor if you have tinnitus. I've been reading the literature on tinnitus for several years, and I have yet to come across a paper that provided data on...
Can Coffee Help My Tinnitus?
Written by AudioNotch Team on June 12, 2015
Categories: Tinnitus Research
Tags: Can Coffee Help My Tinnitus?
Please note: the following information does not constitute professional medical advice, and is provided for general informational purposes only. Please speak to your doctor if you have tinnitus. Understanding Tinnitus Tinnitus is a condition that causes a person to frequently experience a ringing sensation in their...
Notched Sound Therapy - How Strong is the Evidence, Really?
Written by AudioNotch Team on April 6, 2015
Categories: Tinnitus Research
Tags: Notched Music Therapy notched sound therapy Tailor-Made Notched Sound Therapy tinnitus research overview
Please note: the following information does not constitute professional medical advice, and is provided for general informational purposes only. Please speak to your doctor if you have tinnitus. For the average person with tinnitus, making sense of the scientific literature on treatments is a difficult task. Without...
Normal Audiogram Tinnitus
Written by AudioNotch Team on March 21, 2015
Categories: Tinnitus Research
Tags: normal audiogram tinnitus
I've written about this previously here, but I decided to reproduce the article below since it's coming up so frequently: The development of tinnitus has a strong association with hearing loss. The association is so strong that many researchers believe that hearing loss is the most common cause of tinnitus – the...
Acetylcysteine and Tinnitus
Written by AudioNotch Team on March 5, 2015
Categories: Tinnitus Research
Tags: Acetylcysteine and Tinnitus
Tinnitus refers to the condition characterized by sounds heard in the ears that develop secondary to structural alterations. The noise varies from buzzing or ringing to chirping or thumping. The intensity also varies. The sounds may be continuous or intermittent based on possible pressure changes within the ear. Some...
Pilots With Tinnitus
Written by AudioNotch Team on January 17, 2015
Categories: TinnitusTinnitus Research
Tags: pilots pilots and tinnitus Tinnitus
The noise and constant vibrations that are associated with air travel can take its toll on those who fly for a living. Pilots with tinnitus are very common. Pilots are one of the most notorious sufferers of ringing in the ears, a condition that is medically referred to as tinnitus. This condition is at best annoying....
Is there evidence that caffeine can reduce tinnitus volume?
Written by AudioNotch Team on December 31, 2014
Categories: TinnitusTinnitus Research
Tags: caffeine and tinnitus diet and tinnitus
Here is an idea that I've always found intuitively ridiculous: the concept that dietary changes can modify your tinnitus tone volume. Now - most of you are probably aware of "EBooks" that purport to "cure" your tinnitus in an "all-natural" way, usually involved some combination of dietary modifications and new-age...
Tinnitus Frequency Most Common Hz
Written by AudioNotch Team on November 12, 2014
Categories: TinnitusTinnitus Research
Tags: Tinnitus Frequency Most Common Hz
Tinnitus, a chronic ringing in the ears, can be extremely frustrating for its victims. While some people are not negatively affected by this issue, others have serious problems. Anxiety, disrupted sleep patterns, and inability to concentrate are only a few of the issues experienced by those with tinnitus. It's a...
Can an old drug (D-cycloserine) reduce the cognitive side effects of tinnitus?
Written by AudioNotch Team on November 12, 2014
Categories: TinnitusTinnitus Research
Tags: D-cycloserine tinnitus tinnitus research
Extremely interesting new research indicates that some tinnitus patients found a subjective improvement in their cognition when they took D-cycloserine: People with tinnitus perceive ringing in their ears and this phantom noise can cause difficulty concentrating. A new noise doesn’t make the perceived noise go away—but...
Tinnitus may only be curable in an initial 6 week window
Written by AudioNotch Team on November 12, 2014
Categories: Tinnitus ResearchTreatment Review
Tags: furosemide tinnitus
New research on animal models indicates that a commonly used drug, Furosemide, may be effective in treating tinnitus: Six-week treatment window Mulders’ research suggests furosemide is only therapeutically effective in the first six weeks after hearing loss, when auditory neurons appear hyper-excitable. “There is...
Maladaptive Plasticity
Written by AudioNotch Team on November 8, 2014
Categories: TinnitusTinnitus Research
Tags: Maladaptive Plasticity
For centuries, the medical community was under the assumption that once the brain matured, the number of neurons and pathways between these delicate connections were permanent. However, beginning in the 1950s, the theory of neuroplasticity emerged. This theory suggested that among the approximately 100 billion nerve...
Is Tinnitus under-appreciated by the Canadian Military?
Written by AudioNotch Team on October 12, 2014
Categories: TinnitusTinnitus ResearchTreatment Review
Tags: tinnitus veteran veteran tinnitus
A sad case of a veteran unable to acquire effective treatment for his tinnitus: The couple has tried desperately to get help for tinnitus, which is treatable. Back in 2008, Veterans Affairs’ own medical examiner acknowledged that Rainville has tinnitus, and since then, they have been fighting for funding for...
Lidocaine Patch Tinnitus
Written by AudioNotch Team on September 13, 2014
Categories: TinnitusTinnitus Research
Tags: lidocaine lidocaine patch tinnitus tinnitus treatment
Lidocaine patches are sometimes used for pain analgesia, such as for diabetic neuropathic pain. They can be applied locally to the skin and then diffuse into the affected area. There have been reports that intravenous administration of lidocaine can relieve tinnitus temporarily, but lidocaine isn't the kind of drug...
Audio Notch Filter
Written by AudioNotch Team on September 5, 2014
Categories: TinnitusTinnitus Research
Tags: audio notch filter AudioNotch tinnitus filter
What is the Audio Notch Filter and how does it work? Check out the following infographic below to see - focus in on Step 2: The notch filter cuts out one equivalent rectangular bandwith on each side of the tinnitus frequency. The notch filter is based on this study (please note: the Notched Music study used a larger...
Meditation Fixes Tinnitus
Written by AudioNotch Team on August 30, 2014
Categories: TinnitusTinnitus ResearchTreatment Review
Tags: meditation fixes tinnitus meditation tinnitus
Does meditation "fix" tinnitus? A new program called Mindfulness Based Tinnitus Stress Reduction has been studied as a therapy. Instead of directly attacking the volume of the tinnitus tone, this therapy indirectly targets our brain's negative reaction to the tinnitus percept. It's a brilliant technique that leverages...
AM101 Phase 3
Written by AudioNotch Team on August 30, 2014
Categories: Tinnitus Research
Tags: AM-101 AM101 phase 3 clinical trials
AM101, a drug for treating the acute development of tinnitus, is entering Phase 3 clinical trials. Auris Medical today announced enrollment of the first patient into the TACTT2 1 clinical trial. This phase 3 trial will evaluate the efficacy, safety and tolerability of intratympanic injections of AM-101 in the treatment...
Buy AM 101 Tinnitus
Written by AudioNotch Team on August 30, 2014
Categories: Tinnitus Research
Tags: AM-101 buy AM 101 tinnitus Tinnitus
AM 101 is a drug currently in clinical trials for the treatment of tinnitus. A press release explains how it functions: AM-101 is a small molecule N-methyl-D-aspartate (NMDA) receptor antagonist formulated in a biocompatible gel for intratympanic injection. Emerging evidence suggests that NMDA receptors in the cochlea...
Does Tinnitus Go Away?
Written by AudioNotch Team on August 1, 2014
Categories: TinnitusTinnitus Research
Tags: does tinnitus go away? does usually tinnitus go away spontaneous remission Tinnitus
This is definitely a question that's at the forefront of someone's mind if they've just recently acquired the symptom of tinnitus. First things first - if you develop tinnitus: seek the evaluation of a doctor. Some medical causes of tinnitus are reversible and some can be harbingers of serious illness (in rare cases,...
AM-101 Tinnitus Results
Written by AudioNotch Team on July 23, 2014
Categories: TinnitusTinnitus Research
Tags: AM-101 AM-101 tinnitus results tinnitus research
Some of you may be aware of a new drug in development for the treatment of acute tinnitus acquired due to noise trauma. Noise trauma actually kills inner ear hair cells not via direct physical trauma, but via excitotoxicity from an increase in glutamate neurotransmitters. The AM-101 drug is designed to specifically...
McMaster is Running A Music Therapy for Tinnitus Study
Written by AudioNotch Team on June 3, 2014
Categories: AnnouncementTinnitus Research
Tags: mcmaster university music for tinnitus music therapy tinnitus tinnitus music
Good news! If you're in the Hamilton area, McMaster University (my former alma mater) is running a trial of a customized music therapy for tinnitus. Could it be Notched Music Therapy? We'll have to wait and see! McMaster University is currently running a study to test if a customized sound therapy can reduce a person's...
Tinnitus Focused CBT Can Help You Cope With Tinnitus
Written by AudioNotch Team on May 22, 2014
Categories: Tinnitus ResearchTreatment Review
Tags: CBT for tinnitus
Obviously, it's not a cure, but a new article in CNN referencing a new variant of CBT for tinnitus has shown efficacy in reducing subjective distress caused by tinnitus: The study, conducted in the Netherlands, involved 492 patients. Half received an audiological work-up and no other structured treatment, while the...
Predicting Depression after the onset of tinnitus
Written by AudioNotch Team on May 6, 2014
Categories: Tinnitus Research
Tags: depression and tinnitus
An interesting study in 2013 points towards some of the underlying psychological vulnerabilities that may predispose people towards developing depression secondary to tinnitus: Conclusion : Optimism influences depression in tinnitus patients both directly and indirectly. The indirect effect indicates that optimism is...
It's not the tone, it's the brain's reaction to the tone
Written by AudioNotch Team on May 1, 2014
Categories: Tinnitus Research
Tags: tinnitus and neuroticism
The suffering caused by an everpresent tinnitus tone can be broken down into various subcomponents: The loss of concentration from the tone itself Anxiety caused by the tone Depression caused by the tone Psychological distress caused by the tone Insomnia caused by the tone The tone itself is just a tone - it's the...
Vagal Nerve Therapy Trial Recruiting Patients
Written by AudioNotch Team on April 17, 2014
Categories: Tinnitus Research
Tags: clinical trial vagal nerve therapy
An American clinical trial is being launched for Vagal Nerve Therapy for tinnitus. This is pretty exciting news (although the research thus far is limited). A summary below: The new study uses a technique known as vagus nerve stimulation (VNS) that takes advantage of the brain’s ability to reconfigure itself...
TMS Tinnitus
Written by AudioNotch Team on March 27, 2014
Categories: TinnitusTinnitus ResearchTreatment Review
Tags: rTMS tinnitus and TMS TMS Tinnitus
TMS, as it is colloquially referred to (or Repetitive Transcranial Magnetic Stimulation, which is the proper term) has recently been investigated as a possible treatment avenue for tinnitus. A lot patients get excited about TMS & tinnitus, but the results have not been good. People are attracted to TMS because it's...
More on the Michigan Research
Written by AudioNotch Team on February 6, 2014
Categories: TinnitusTinnitus Research
Tags: dorsal cochlear nucleus tinnitus
There's a fantastic article available that provides a great overview of the research that's coming out of Michigan. This research is exciting because it offers a possible avenue for treatment. Susan Shore, the senior author of the paper, explains that her team has confirmed that a process called stimulus-timing...
Another Paper from the Pioneers of Notched Music Therapy for Tinnitus
Written by AudioNotch Team on February 4, 2014
Categories: HearingTinnitusTinnitus ResearchTreatment Review
Tags: Notched Music Notched music therapy tinnitus
The original discoverers of Notched Music therapy have released another paper that provides an excellent theoretical overview of the conceptual underpinnings of the therapy. Rather than rehash what the authors have already done a great job of writing about, I'll post the abstract below: Over the past 15 years, we have...
Laser Therapy as a Treatment for Tinnitus?
Written by AudioNotch Team on January 2, 2014
Categories: Tinnitus ResearchTreatment Review
Tags: laser therapy for tinnitus tinnitus review tinnitus treatment
I'm not entirely sure what to make of this, because I can't postulate a mechanism for why this might work. But consider the following description of a tinnitus treatment: Subjects in the intervention group underwent laser therapy for 20 sessions, every other day, 20 minutes each session, which was a combination of...
What About Failed Drug Treatments for Tinnitus?
Written by AudioNotch Team on December 31, 2013
Categories: Tinnitus ResearchTreatment Review
Tags: Tinnitus tinnitus treatment L-baclofen
One of the issues plaguing scientific research is the tendency to avoid publishing negative study results - i.e. if something DIDN'T work, people are far less prone to publish a scientific paper about it. That's why it's heartening to see research like this, on why L-baclofen doesn't appear to work in animal models of...
Childhood Tinnitus: What Do We Know
Written by AudioNotch Team on December 26, 2013
Categories: Tinnitus Research
Tags: tinnitus and children
Childhood tinntius is less common than tinnitus among adults. The profile of tinnitus causes in children seems to quite different for children. For example, myoclonus seems to be a much more common cause. Reviewing the abstract doesn't reveal that much: PURPOSE: Troublesome tinnitus in children can have an impact on...
Chronic Tinnitus Treated with Drug in Animals
Written by AudioNotch Team on December 19, 2013
Categories: TinnitusTinnitus Research
Tags: chronic tinnitus NMDA receptor antagonist Tinnitus tinnitus reserach
Animal models have proven to be a fruitful avenue of research for tinnitus treatment (and I say fruitful in the sense that we've learned things - there aren't currently any tinnitus specific drugs that have made it to market for chronic tinnitus). Many of these drug treatments have focused on drugs for acute onset...
Promising Early Results for Vagal Nerve Therapy for Tinnitus
Written by AudioNotch Team on December 5, 2013
Categories: Tinnitus Research
Tags: Tinnitus vagal nerve therapy vagal nerve therapy tinnitus
Encouraging results have been reported in a small trial of vagal nerve therapy for tinnitus : UT Dallas researchers have demonstrated that treating tinnitus, or ringing in the ears, using vagus nerve stimulation-tone therapy is safe and brought significant improvement to some of the participants in a small clinical...
Tinnitus and Neuroticism, Part 2
Written by AudioNotch Team on October 2, 2013
Categories: TinnitusTinnitus Research
Tags: tinnitus and neuroticism tinnitus research
A press article summarizes findings about the relationship between neuroticism and tinnitus in an accessible framework: People with 'neurotic' tendencies are more likely to be troubled by their tinnitus, a new study involving researchers at The University of Nottingham, has found. The research, led by academics at the...
Study Suggests Tinnitus Significantly Disrupts Sleeping
Written by AudioNotch Team on September 20, 2013
Categories: Tinnitus Research
Tags: tinnitus and insomnia tinnitus and sleep tinnitus sleep disruption
There is plenty of anecdotal evidence that tinnitus causes increased sleep latency and insomnia. What's surprising to me is this recent study, which seems to suggest that tinnitus patients may suffer from disruption of multiple sleep stages, including a significant reduction in REM sleep : All tinnitus patients had a...