The AudioNotch Tinnitus Treatment Blog

Please note: the following information does not constitute professional medical advice, and is provided for general informational purposes only. Please speak to your doctor if you have tinnitus.

For people who suffer from inner ear disorders such as tinnitus, life can be anything but pleasant. A constant ringing, hissing, or roaring sound, the disorder can have a severe impact on a person’s ability to lead a normal life. Whether it’s an inability to sleep, concentrate, or simply relax, tinnitus is without a doubt one of the most frustrating conditions anyone can deal with on a daily basis. However, for those who suffer from tinnitus, the good news is companies such as Auris Medical have made great strides in tinnitus research.

AM-101
Having conducted numerous clinical trials regarding tinnitus, Auris Medical has recently developed a very promising treatment known as AM-101. Designed to help those who have tinnitus as a result of a traumatic cochlear injury, AM-101 is formulated into a fully biodegradable gel. Administered in one treatment cycle consisting of 3-5 injections, it is deemed to have an excellent chance of becoming the first drug to gain approval for treating inner ear tinnitus.

Research Effectiveness
What has made this clinical trial so promising for patients is the effectiveness of the treatment. Based on initial results, patients who participated in the clinical trials reported having improvements in tinnitus loudness, sleep difficulties, and many other aspects of tinnitus. In fact, in some instances more than 62 percent of patients reported dramatic improvements with managing their tinnitus.

Clinical Trials and Safety
When it comes to clinical trials, safety is of the utmost priority, and it is no different with Auris Medical. Using non-clinical toxicology and tolerance studies, AM-101 has been shown to have no negative impact on person’s hearing or balance, even when given at high doses. Because of this, researchers now believe that repeated and concentrated treatments with AM-101 have the potential to greatly reduce or possibly even eliminate tinnitus in many patients.

Additional Research
With such promising results from these clinical trials, Auris Medical expects to conduct further studies to determine just how AM-101 can work with patients to relieve them of their debilitating conditions. Additional research is expected to focus on the relationship between tinnitus and auditory nerves, along with how NMDA receptors impact or suppress the auditory nerves during bouts of tinnitus. As results from the clinical trials become more well-known, it’s expected Auris Medical will have more and more patients eager to take part in future research studies. According to most researchers, this will no doubt lead to many additional discoveries about how tinnitus can be treated.